Fr I am curious now how it would actually be handled on house. I could see maybe an episode where hormone therapy being a red herring and all the debates the staff have. House with poor bedside manner with trans issues without being transphobic, Watson and Cameron being super sweet to overcompensate. Chase is insensitive but accepting,, he laughs and jokes around with stuff in the patient's house. Foreman is tolerant but secretly uncomfortable. Cuddy yells at house.
Oh no, House always has to screw it up 3 times before getting it right. And it's never a reasonable thing, you'd get treated for lupus for some reason.
Sam and Max immediately act like you're trans. There is no realization, just an off-handed quip. Sam takes one of your lightbulbs, and the world becomes notably worse less than a day later.
Jessica Jones calls you an idiot for not realising you're trans, but she does it out of earshot and then offers you some beer from the bottle she's drinking out of.
Jessica Fletcher would figure it out when she dressed up as a drunk to tail her niece. She'd sing a bit of shanty, kiss you on the forehead, and encourage you to be yourself. You were once her student, and she always knew from your writing that you were a kind soul and a wicked plot weaver.
Jessica Fletcher actually causes you to question your entire identity several weeks before suddenly hopping on a train and attending a book signing event she set up without her publicist knowing. Then when she arrives she bumps into one of your friends nowhere near the signing event, manipulates the conversation into talking about you, figures out where you work, shows up and claims that she was just passing by. After a couple days of back and forths while she tells everyone within earshot it was such a coincidence she was there at that time she, quite literally the night before her departure, tells you your life story and convinces you on the spot that you are indeed trans.
The csi team deduce you are trans by the fact that the bloodied corpse of the star cheerleader is making you so mad not because you wanted to be with her but because you wanted to be like her.
Detective Costeau hasn't figured it out yet, you haven't even met him yet, he's still sleeping off his last bender. Kim, on the other hand, already had your pronouns in his notes alongside a comprehensive psych eval
Rust Cohle sees you and has a vision about the vast emptiness of space, where he realizes that life has no meaning and time just repeats endlessly in an inescapable loop. He numbs himself every night trying to forget you, but he can’t escape the gravity of your memory. He’s pulled under the darkness, like a crashing ocean wave, and he’s drowning, over and over, in the inky blackness. He realizes you’re trans five years later, after everything he loves is dead, because he’s the only one who can.
Frank Drebin ramraids your front door, notes that you live with no front door, figures out you're quirky because nobody leaves the door open these days.