Unarmed build is great fun. Unarmed Courier Six walked into Caesar's camp guarded by few hundred strong warrior and proceed to punch Lanius to death making Courier Six the most powerful MC of Fallout universe.
The idiots give you back your guns if you play along to "put the platinum chip into the bunker" , then you shoot them in the face, go to Caeser, and shoot him in the face too.
spoiler
No one clocks any of this because they're seperate maps. then you walk out of there, until the guard by the door tells you that you cannot leave with the platinum chip.
Because Unarmed is fun! Early on it might be not so good as you have to make do with nothing or a boxing glove that would quickly wear out, but mid game when you get perks like Super Slam, slayer, and piercing strike, you became an unstoppable force.