Novel drug could treat long COVID and prevent re-infection
Novel drug could treat long COVID and prevent re-infection
A new drug developed by QIMR Berghofer could transform the treatment of COVID-19 by potentially protecting against infection by any SARS-CoV-2 variant and reversing the persistent inflammation that is a major driver of debilitating long COVID.
A new drug developed by QIMR Berghofer could transform the treatment of COVID-19 by potentially protecting against infection by any SARS-CoV-2 variant and reversing the persistent inflammation that is a major driver of debilitating long COVID.
It's worth noting that it is not currently known whether or not reducing inflammation will have a significant impact on long Covid symptoms. Research is still being done in that area.
I'm lucky enough (such as that may be) to not have, or know anyone personally who has, long COVID, so the first person that came to mind for this was YouTuber "Physics Girl" Dianna Cowern.
If other sufferers are as debilitated as she appears to be, and it helps in any way at all, this drug is fantastic news.
If it can "fix" someone completely, even if it's a lifelong medication, even better.
My husband has ME/CFS, like the Physics Girl. It's an absolutely devastating illness. He was a very active 35 when he was told there's no cure, not even a treatment, and that pain/fatigue was his life now for the rest of his days.
We've been around this long enough to see promising drug/cure/treatment/diagnostic tests come and disappear, month after month, year after year. The influx of funding/awareness linked to Long Covid is incredibly welcome, but many instances are repeats of previous ME/CFS research, so it holds up previous findings but doesnt drive anything forward. There's not been any real progress in the last 2 years, and the funding/focus is waning. I may be jaded, but hopes are low. I also sincerely hope I'm wrong.
There's no treatment that's close to a cure, but my symptoms are improved by a combination of high dose Coenzyme Q10 and creatine, along with Mestinon for orthostatic intolerance. I'm working with a team at Brigham & Women's in Boston, led by Dr. David Systrom, that is exploring the idea of mitochondrial dysfunction as the underlying pathophysiology. Last year I participated in a phase I clinical trial of a new drug targeting a mitochondrial receptor, but we're still waiting for those trial results to be released.
This particular team is doing invasive cardiopulmonary exercise testing (iCPET) as diagnostics, if you've not had that explored yet. It didn't give me much in the way of treatment options beyond what I mentioned above, but at least it's given me some semblance of hard data to provide legitimacy when explaining my condition to people.
I only mention because I'm not particularly active in the ME/CFS circles because of the high volume of disappointing red herrings, so I'm not sure how well known this path of inquiry is.
I'm so sorry.
Despite no close-to-home stake, I'd also really like it if you were wrong.
That's who I thought of as well. I check her channel periodically hoping to see the "I'm back" video. No luck yet :(
I hate to say it, but while hopeful, it's unlikely.
I've been around the CFS/ME community since my husband got it 6 years ago. There a small handful of people who have recovered, but generally they've been "misdiagnosed" with CFS and then correctly diagnosed/treated. The majority live with it for the rest of their lives. It's also why the life expectancy is only 50 - many simply cannot live with that level of pain/suffering day in, day out without any real hope of improvement/relief. Its a dreadful illness.
I think this is the Nature Communications article cited in the OP link:
https://doi.org/10.1038/s41467-023-39341-4Notice the credit for this article at the bottom:
Provided by QIMR Berghofer
So this really seems to be a press release from the company, not an independently written article.