When will the patches be stable enough that one would -with a reasonable degree of certainty- no longer expect save corruption anymore in the process? Because I will not, can not, do the first couple hours yet again at this point. I may roll another character when things have settled down and any further twiddling will be mostly cosmetic, but right now, no. BG3 is on hold for me now.
I don't think it's a cause for concern. There was a hotfix right after launch that affected some people's saves, I think, (I haven't encountered any issues) and they immediately rolled it back. They've released one major patch so far, and I haven't seen any complaints about savegame integrity. I didn't play DOS2 at launch so I can't speak to the history there, but I'd be very surprised if save corruption was an issue with this game. They've got a zillion people playing it right now, the last thing they want to do is piss them all off.