Grapefruits are already man-made hybrids of others fruits. Hybridizing fruit is way less complex and way more safe than tweaking medication and trying to get it approved.
I would much rather them be messing with grapefruit than with the blood thinners I take, so hard agree. Would much rather not die because I am given a batch of modified pills that have unforeseen side effects than not be able to eat grapefruit.
It's a grapefruit x mandarin hybrid. We've been cross-breeding species for, well, ever. Some foods you're familiar with may be hybrids and you don't even realize it
Apples are different. Apple seeds from a particular tree will grow some other kind of apple. The seeds are genetically different from the parent tree, and most of them are not tasty. The ones that turn out to be tasty are grown into new plants from cuttings.
Grapefruit interacts with specific metabolic pathways in the liver. Most medications are broken down by the liver. That's just how the body works, unfortunately
I naively thought it would be easier to change the make-up of the medication rather than the make-up of a fruit but from some of the replies here, I can see the upside of changing the fruit as well.