I think it is a reference joke to when YouTuber Linus from linus tech tips expressed remorse for having formerly used the "hard R" during a podcast, mistaking it for the word "retarded". The video of it, including the panic and awkward clarification that ensued, went viral on tech circles as cringe inducing amusement and proof of Linus's social ineptitude.
The way he figures out what he meant and thinks about the smartest way to ask for clarification cracked me up. He goes through like 4 emotions in 10 seconds