How do you containerize stuff you install from source in a way that you can completely remove later?

I'm doing a bunch of AI stuff that needs compiling to try various unrelated apps. I'm making a mess of config files and extras. I've been using distrobox and conda. How could I do this better? Chroot? Different user logins for extra home directories? Groups? Most of the packages need access to CUDA and localhost. I would like to keep them out of my main home directory.