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NIH funded a project to manipulate coronaviruses in Wuhan so they would be able to infect humans

web.archive.org /save/https%3A%2F%2Fwww.nih.gov%2Fsites%2Fdefault%2Ffiles%2Finstitutes%2Ffoia%2F2R01AI110964-year-6-tranche-05.pdf

According to the document:

  • The project involved, among other tasks, performing gain-of-function on bat coronavirus SARSr-CoV WIV1, with the aim of studying its potential ability to infect humans.
  • The researchers believed regulations on gain-of-function research did not apply in this case, since the original virus did not affect humans, despite the desired product virus being able to do so.
  • Their risk assessment does not include the possibility of the newly created virus accidentally infecting workers or human research subjects.
  • The resulting viruses were to be tested on both human tissues and modified mice with human ACE2 enzyme.
  • Human subjects from "high-risk areas" were involved on-site for non-experimental purposes.
  • These experiments were performed within facilities of the Wuhan Institute of Virology.
  • The phase of the project wherein these experiments were first mentioned started on June 2019.

Additionally, this adds:

  • The entire project started in June 2014 and initially involved collecting virus samples from different sources, including the wildlife market in Wuhan.
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