Inhibition of IL-11 signalling extends mammalian healthspan and lifespan - Nature
Inhibition of IL-11 signalling extends mammalian healthspan and lifespan - Nature
www.nature.com Inhibition of IL-11 signalling extends mammalian healthspan and lifespan - Nature
IL-11 is identified as a key regulator of ERK–AMPK–mTORC1 signalling, metabolism, inflammation and age-related disease and lifespan in mouse and human.
Here we examined whether IL-11, a pro-inflammatory cytokine of the IL-6 family, has a negative effect on age-associated disease and lifespan.
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