Part of the reason why WW2 didn't spark the same level of anti-German backlash is because many who were beginning their political careers during WW1 were horrified at the anti-German bigotry that arose during WW1; and thus when WW2 came around, made sure to portray the WW2 German government as tyrannizing the German people, rather than synonymous with them.
Apparently, though, that wasn't a concern for Japanese-Americans, who got to 'enjoy' the weight of US 1940s racism.
I sometimes feel that when we as humanity try to learn some lessons from the past we act like a jinn taking wishes too literally. Like okay, now if that's a German citizen, in the USA, we're going to treat them okay. We will not if that's not the USA (like the UK did), or not German ¯\_(ツ)_/¯
Far fewer, not systematically; mostly unnaturalized immigrants and those with connections to the Italian government. Many of them were released before the war's end. But yes.