Specifically 46,XY with CAIS, causing a total lack of response to androgens, and since those are what tell a fetus to develop male bits instead of defaulting to female bits...
That's because this topic is in special focus today, for you and many others. But it's really not different to treating someone shitty for any other reason they can't do anything about, like being bald or small or whatever.
It's just always shitty to treat people shitty, it's not a contest who least deserves to be treated shittily.