Dunno, create a script that uses a program to get the process number of the current active window or the window the mouse is hovering, and then kill that? Bind that script inor a key with whatever program and voilá.
Get learning lol. I know that there's some command line program that gives process info on mouse hover and then that can be parsed with awk to get the pid, then pipe that again into kill -kill. Then use xbindkeys or whatever keybindings program to bind that script to a key.
Tbh. For involved stuff like this chatgpt will help you more than stackoverflow.