40-45C happens in our summers on a semi regular basis (thank f*** last summer we only had a handful of days like that). Inner Oz can reach close to 50C in some areas.....
I've done low humidity 45° days/38° nights and it was pretty toasty, but 35° with high humidity kicks my arse. The last couple of weeks here in Catalunya we've had 30-35° with high humidity and I'm just exhausted.