I am genuinely surprised that AI has not already been used to discover countless drugs all with chemical properties that are different and not illegal. It will come of course at some point likely before the end of the decade but who knows. I suspect that there will be some pretty awesome drugs that have e lower side effects and or there will be counter measures discovered to offset negatives etc.
We don't need AI, we've had those chemicals for decades. They're called Research Chemicals and some countries (like the UK I think) preemptively ban them, while in others they have to be explicitly banned. It's an ongoing cat and mouse game, but if you asked me I'd rather take a well known compound and not some random crap that was invented last year and like 6 people took.
The awesome drugs with lower side effects are the well known ones, like LSD.
I did a research chemical that was supposed to be like LSD, called 2C-P.
May or may not be legal depending on where you live, but I'd be weary of doing it again. I overheated like a motherfucker. And although it was potent, it didn't feel like a clean high you get with LSD.
I agree with the other poster. I'd much rather do drugs that have a long, proven history as opposed to something that is relatively unproven.