Cassava: The perilous past and promising future of a toxic but nourishing crop

The three staple crops dominating modern diets – corn, rice and wheat – are familiar to Americans. However, fourth place is held by a dark horse: cassava.

While nearly unknown in temperate climates, cassava is a key source of nutrition throughout the tropics.

Cassava’s many assets would seem to make it the ideal crop. But there’s a problem: Cassava is highly poisonous.

One of cassava’s most important strengths, its pest resistance, is provided by a powerful defense system. The system relies on two chemicals produced by the plant, linamarin and linamarase.

These defensive chemicals are found inside cells throughout the cassava plant’s leaves, stem and tubers, where they usually sit idle. However, when cassava’s cells are damaged, by chewing or crushing, for instance, the linamarin and linamarase react, releasing a burst of noxious chemicals.

One of them is notorious: cyanide gas. The burst contains other nasty substances as well, including compounds called nitriles and cyanohydrins. Large doses of them are lethal, and chronic exposures permanently damage the nervous system. Together, these poisons deter herbivores so well that cassava is nearly impervious to pests.