Fructose may be the ultimate driver of obesity
Fructose may be the ultimate driver of obesity
Recent research implicates fructose in suppressing cellular energy production and driving fat accumulation in the body.
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No. Still calories.
I constantly see people bickering about this online, but that's not at odds with CICO. Yes, the overarching limits is CICO, but most people don't track calories. Fructose makes you more hungry and so you eat more food, and therefore CICO means you gain weight. From the article:
When these cellular powerhouses are slowed, the cells get stuck in a low-energy state, triggering hunger and thirst
So you're correct, but it's an unhelpful response. Kind of like saying "No, the Earth still isn't flat" when people are trying to figure out exactly how round it is.
EDIT: To your other comment:
At no point is fructose a direct cause of obesity, a byproduct yes.
"direct cause" is the wrong way to look at this. Even if the mechanism by which it acts doesn't cause obesity itself, it can be a root cause if, without it, people wouldn't engage in behaviors that lead to obesity, i.e. overeating. The difference between "he died because he ran into a tree" vs "he died because he was texting and not paying attention".
It really isn't this complicated. You are obese because you do not count calories. End of discussion. External factors of a bad diet are entirely your fault. Personal responsibility is the only outcome for becoming healthier. Calorie counting and adherence are 90% of being not obese. Everything else is supplementary. Fructose is far from the problem, nor is it even as bad as this trash research wants to make believe.
I do not count calories and eat until I'm full. Yet I'm not obese, not even overweight. In fact, if I had to become obese, I'm not sure that I physically could. How does a theory of "personal responsibility" explain that?
Obesity is caused by some neurochemical fuckery that affects hunger and/or metabolism. That is a fact, supported by science, though the exact mechanisms are still very badly understood (in large part due to lack of funding for decades, caused by a completely misguided dogma that obesity is a moral failing). If it was all a willpower thing then how come some medications make people lose or gain significant weight?
(Yes, you can gain or lose weight by counting calories. However, every step of the way, you will be fighting your own body's attempts to go back to its baseline, even if that baseline is very unhealthy. Of course in the absence of a better solution it's better to lose weight by counting calories than staying unhealthy, but please realize that you're in deep with the Dunning-Kruger effect and stop disparaging medical science).
Just because you are not actively counting, doesn't mean you aren't at maintenance or below. The vast majority of morons that are incapable of understanding basic thermogenics and the fact that if your body is fueled less than it needs it will draw from stored adipose lipids and if fed more than needed it goes back into storage, are just coping beyond anything.
Obesity is not caused by your desire to eat. It is caused by your inability to stop eating. End of discussion. Metabolism is a buzzword to describe people too lazy to understand basic concepts. Look in any gym and the people who maintain willpower to eat less and focus on energy intake are the quickest to achieve results. There are reasons that losers looking for the easy way to weight loss never receive longterm results. This isn't a "well um yes you can gain or lose weight through calories" it's literally the ONLY way. Even hormone imbalances only increase or decrease your need for intake. This is something understood since the Spartans who would eat less if they noticed any fat gain in their physiques. There's a reason every single diet based in fact will tell you to spend 3 months in a deficit and 2-3 months in a ned maintenance, to establish the new baseline. This is a marathon not a sprint. You're the only one disgracing "medical science" by trying to overcomplicate a very simple concept.
Please, for the love of god, get your macho douche-bro ass energy out of here.
"Obesity is not caused by your desire to eat"
"even hormone imbalances only increase or decrease your need for intake"
the fact that you don't see these two sentences as hilariously contradictory shows how circular your entire reasoning is. So close to getting the point, yet so far.Zzzzzzz. Cope.
You do not want to understand the complexity of things like bioavailability, disruption of regulatory systems like faulty hunger signals and absorption, etc. You might as well be saying that drugs don't don't influence behavior.
Tell people to own their own faults and if they want change look inward instead of for confirmation biased articles rooted in bad data: "erm no its not my fault I just have a thyroid problem and also my brain is telling me im hungry and I HAVE to listen and also um I just erm um"
Cope. Millions of people have fixed their weight issues and it wasn't through anything but a controlled diet.
Source please
Oh I don't know, any respected dietician or nutritionist just telling you to focus on macronutrient balance to get the proper 500 calorie deficit from maintenance to lose 1 pound a week?
Or maybe https://pubmed.ncbi.nlm.nih.gov/18025815/
Or https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8017325/
Or https://www.hsph.harvard.edu/news/press-releases/diets-weight-loss-carbohydrate-protein-fat/
Maybe stop looking to psuedo-science that just wants to sell you a product, meal plan, or supplement and just accept it's very basic. This fucking thread article literally says he wants to develop and sell a drug to counteract fructose. Or maybe just maybe take some accountability and just enjoy fructose containing foods in a caloric moderation and boom you're not obese. This is BASIC thermogenic energy management. 90% of a healthy diet is consistency in caloric intake. The rest regarding timing, macros, micros, food quality are all supplementary to reach your goals. But setting being NOT OBESE as the BARE MINIMUM GOAL, it's so fucking easy to just reduce daily calories.
From your second link:
Our review indicated that there is no single best strategy for weight management
Obesogenic environments and biological and psychological factors all contribute to obesity.
However, energy intake and energy expenditure are dynamic processes influenced by body weight and influence each other. Thus, interventions aimed at creating an energy deficit through the diet are countered by physiological adaptations that resist weight loss.
Moreover, metabolic adaptations to decrease energy expenditure can lead to a plateau with this type of diet, which individuals may misinterpret as “failure” due to “lack of willpower.”
See? The scientists you quoted took a stab at you
"According to a meta-analysis of several diet programs, calorie restriction was the primary driver of weight loss, followed by macronutrient composition." It's like your reading comprehension is designed to just find your own biases and accept them unequivocally. Cope.
Look in the mirror
You're acting like it's trivial. Obesity wouldn't be common if it was trivial
Your own sources says why it's hard and you're pretending you didn't see it
Nah mate you're delusional. If we're talking the LOWEST BAR POSSIBLE: don't be obese. It's so simple to just intake less calories. We're not saying lose body fat, get into shape, become an athlete, or 12% bf. Just literally set your bmi ( a bullshit measurement anyway) to AT MINIMUM overweight.
Yes it's ludicrously trivial and requires you to just stop eating so much. The same fucking method vets have your dog do when they weigh too much.
As I said elsewhere, calories and consistency are 90%, everything else is to optimize your goal. And the vast majority of people are lazy morons who can't stay consistent.
Everyone needs calories, no one needs fructose.
What kind of statement is this. Calories are not comparable to the macronutrients that make them. Secondly, fructose (the worst of sugar) still isn't even dangerous unless in extreme amounts. It is objectively overeating calories, whether they be from protein fats or carbs, that make people obese. Objectively. At no point is fructose a direct cause of obesity, a byproduct yes.
Saying "People are obese due to calories" is about on the same level as "Cars crash because they move" or "Your floor is dirty because you spilled coffee". It's entirely correct, but it's also pretty useless.
"Eat fewer calories" is advice that's on the same level as "Next time, instead of dropping your coffee, don't drop it". It's true, and it works, but it's also useless since that's just not how it works. Why does someone overeat? Do they not know something is bad? Do they feel hungry all the time because of their diet? Are they eating shit because they don't have time/knowledge/ability to cook? Did I drop my coffee because I sneezed? Did I trip over the cat? Is my floor full of random holes? Am I wearing rollerscates? The nuances make all the difference, and the nuances are what you can use to improve the situation.
"If you don't want to crash, do not press the accelerator" is not road safety advice. "Make sure you keep your distance and check your brakes" is road safety advice.
Lmao, such a reach to defend people being too lazy to count calories. Dieting isn't this complicated and if you're fat, it's 100% your fault.
I'm sure you need to tell yourself that to have people you can feel superior to
Cope